G-Mycin 250mg (Azithromycin)

1. Product Description

2. Chemical Information

3. Indications

Primary Uses:
- Treatment of respiratory infections (e.g., bronchitis, pneumonia)
- Treatment of skin infections (e.g., cellulitis, impetigo)
- Treatment of sexually transmitted infections (e.g., chlamydia, gonorrhea)
- Treatment of ear infections (e.g., otitis media)
- Treatment of certain throat infections (e.g., pharyngitis, tonsillitis)

4. Dosage and Administration

Dosage Form:
- 250 mg Capsules: Typically used in a variety of infections.
Typical Dosage Schedule:
- 250 mg: Dosage may vary based on the infection being treated. Commonly prescribed as a single daily dose for 3 to 5 days, or as directed by a healthcare provider.
Administration: Swallow capsules whole with a full glass of water. Do not crush, chew, or break the capsules.

5. Pharmacokinetics

Absorption: Azithromycin is well absorbed from the gastrointestinal tract. Peak plasma concentrations are generally reached within 2 to 3 hours after oral administration.
Distribution: Widely distributed throughout body tissues, with high concentrations in tissues such as the lungs, tonsils, and skin.
Metabolism: Metabolized primarily in the liver.
Excretion: Excreted mainly in bile and feces, with a small amount in urine.

6. Side Effects

Common Side Effects:
- Gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea)
- Abdominal pain
- Headache
Serious Side Effects:
- Risk of severe allergic reactions (e.g., rash, itching, swelling, difficulty breathing)
- Risk of liver issues (e.g., elevated liver enzymes, hepatitis)
- Risk of heart rhythm problems (e.g., QT prolongation)
- Risk of Clostridium difficile infection in the colon

7. Contraindications

Known Allergies: Hypersensitivity to azithromycin, other macrolide antibiotics, or any component of the formulation.
Liver Disease: Caution in patients with severe liver impairment.

8. Precautions

Caution: Use with caution in patients with a history of liver disease, kidney impairment, or those who are pregnant or breastfeeding.
Drug Interactions: May interact with other medications, including those affecting liver enzymes (e.g., warfarin, certain antifungals). Inform your healthcare provider about all medications you are taking.
Monitoring: Monitor for signs of allergic reactions and potential liver or heart issues, particularly in long-term use.

9. Storage

Conditions: Store at room temperature, away from moisture and heat.
Packaging: Typically available in blister packs or bottles with child-resistant caps.

10. Patient Counseling Information

Report Symptoms: Notify your healthcare provider if you experience severe side effects or signs of an allergic reaction.

Adherence: Complete the full course of treatment as prescribed, even if symptoms improve before finishing the medication.

Timing: Take as directed, usually once daily.

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