Gelcaps

G-Mycin 250mg (Azithromycin)

G-Mycin 250mg (Azithromycin)

1. Product Description

  • Name: G-Mycin 250mg (Azithromycin)
  • Type: Macrolide Antibiotic
  • Form: Oral capsule
  • Strength: 250 mg per capsule

2. Chemical Information

  • Chemical Name: Azithromycin
  • Molecular Formula: C38_{38}38​H72_{72}72​N2_{2}2​O12_{12}12​
  • Molecular Weight: Approximately 749.98 g/mol

3. Indications

  • Primary Uses:
    • Treatment of respiratory infections (e.g., bronchitis, pneumonia)
    • Treatment of skin infections (e.g., cellulitis, impetigo)
    • Treatment of sexually transmitted infections (e.g., chlamydia, gonorrhea)
    • Treatment of ear infections (e.g., otitis media)
    • Treatment of certain throat infections (e.g., pharyngitis, tonsillitis)

4. Dosage and Administration

  • Dosage Form:
    • 250 mg Capsules: Typically used in a variety of infections.
  • Typical Dosage Schedule:
    • 250 mg: Dosage may vary based on the infection being treated. Commonly prescribed as a single daily dose for 3 to 5 days, or as directed by a healthcare provider.
  • Administration: Swallow capsules whole with a full glass of water. Do not crush, chew, or break the capsules.

5. Pharmacokinetics

  • Absorption: Azithromycin is well absorbed from the gastrointestinal tract. Peak plasma concentrations are generally reached within 2 to 3 hours after oral administration.
  • Distribution: Widely distributed throughout body tissues, with high concentrations in tissues such as the lungs, tonsils, and skin.
  • Metabolism: Metabolized primarily in the liver.
  • Excretion: Excreted mainly in bile and feces, with a small amount in urine.

6. Side Effects

  • Common Side Effects:
    • Gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea)
    • Abdominal pain
    • Headache
  • Serious Side Effects:
    • Risk of severe allergic reactions (e.g., rash, itching, swelling, difficulty breathing)
    • Risk of liver issues (e.g., elevated liver enzymes, hepatitis)
    • Risk of heart rhythm problems (e.g., QT prolongation)
    • Risk of Clostridium difficile infection in the colon

7. Contraindications

  • Known Allergies: Hypersensitivity to azithromycin, other macrolide antibiotics, or any component of the formulation.
  • Liver Disease: Caution in patients with severe liver impairment.

8. Precautions

  • Caution: Use with caution in patients with a history of liver disease, kidney impairment, or those who are pregnant or breastfeeding.
  • Drug Interactions: May interact with other medications, including those affecting liver enzymes (e.g., warfarin, certain antifungals). Inform your healthcare provider about all medications you are taking.
  • Monitoring: Monitor for signs of allergic reactions and potential liver or heart issues, particularly in long-term use.

9. Storage

  • Conditions: Store at room temperature, away from moisture and heat.
  • Packaging: Typically available in blister packs or bottles with child-resistant caps.

10. Patient Counseling Information

Report Symptoms: Notify your healthcare provider if you experience severe side effects or signs of an allergic reaction.

Adherence: Complete the full course of treatment as prescribed, even if symptoms improve before finishing the medication.

Timing: Take as directed, usually once daily.